Scientists have developed a male contraceptive pill that does not contain hormones, which prevents sperm from traveling to the sperm. Male contraceptive pill prototype stops sperm swimming Published.
This will solve the problem that birth control used to be reserved for women because the only way to help men with birth control was condoms and condoms.
A new type of male penis is promising, as reported in the journal Nature Communications.
An experiment conducted on mice showed that a single ‘dose’ of this drug, known as ‘TDI-11861’, captures sperm and stops them before, during, and after sexual intercourse they are unable to meet the female egg.
Researchers have shown that this phase lasts for three hours when the sperm cannot travel to meet the sperm, but after 24 hours another round of sperm is alive as usual.
While these pills work well for humans, men can take them as needed or daily to prevent pregnancy.
These pills may not protect against sexually transmitted diseases. Then people will continue to use condoms.
Experts say these pills should be tested on rabbits before being given to humans.
Female birth control pills usually contain hormones, but male birth control pills do not. Male contraceptive pill prototype stops sperm swimming Published.
Scientists say that it will not have any effect on men because this substance is intended to bind or bind to the sperm cell known as ‘soluble adenylyl cyclase or sAC’.
In the early study in mice, funded by the US National Institutes of Health and published in the journal Nature Communications, a single dose of the drug, called TDI-11861, immobilized sperm before, during, and after mating.
The effect lasted for around three hours. By 24 hours, it appeared to have fully worn off with the next batch of sperm swimming normally.
One of the scientists, Dr. Melanie Balbach from Weill Cornell Medicine in New York, said it showed promise as a reversible, easy-to-use contraceptive.
If it does ultimately work in humans, men might be able to take it only when, and as often, as needed. They could make day-to-day decisions about their fertility.
But it would not protect against sexually transmitted infections, experts warn. Condoms would be needed for that.
Prof Allan Pacey, professor of andrology at the University of Sheffield, said: “There is a pressing need for an effective, reversible, oral contraceptive for men and although many different approaches have been tested over the years, none has yet reached the market.
“The approach described here, to knock out key enzyme in sperm that is critical for sperm movement, is a really novel idea. The fact that it is able to act, and be reversed, so quickly is really quite exciting.
“If the trials on mice can be replicated in humans with the same degree of efficacy, then this could well be the male contraceptive approach we have been looking for.
“They have done some tests on human sperm in the laboratory and it works in exactly the same way. So that, I think, really does open up the prospects that we can have some human trials.”
Meanwhile, other researchers have been looking at a slightly different pathway to halt sperm swimming, by blocking a protein on the surface of sperm.
